Archive for the ‘Anxiety’ Category

https://www.sciencedaily.com/releases/2018/09/180910173731.htm

Very effective medication for many conditions.

AuntieBS

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https://www.sciencedaily.com/releases/2018/04/180419100110.htm

Another useful data point.

AuntieBS

https://www.sciencedaily.com/releases/2018/02/180215153923.htm

This paper cites the need for more, controlled research into medical cannabis uses and no one would argue that, but their usage and conclusions are questionable.  First, for pain relief, cannabis has an interesting property.  It only reduces pain slightly, but renders the patient not caring about it, thus making the pain more tolerable.  Unrealistic expectations also can interfere with analgesic properties.  Given cannabis’ sedative effects, it is often best used at night, when opiates would wear off, waking the patient, while cannabis lasts the night through.  Cannabis should be administered orally for a longer, time-release, effect, with 1-3 hours (2 typ) allowed before effects begin.

Further, some of the pain relief may be through defacto hypnosis, since cannabis can be considered a hypnotic drug, and therefore be heavily modulated by the patient’s mindset.  Inexperienced patients may feel anxiety, thereby rendering cannabis less effective for pain and sleep.

It is important for the prescribing physician to determine the patient’s familiarity and experience with cannabis before prescribing, as such patients often know subjectively how well it works for them.  Novice patients need be counseled on what cannabis does and does not do, with sufficient disclaimers so as to not give unrealistic expectations.  “This may make it easier for you to sleep through the pain and you might experience a bit of dizziness if you get up at night”, would be appropriate advice.  Note that pain is not mentioned.  “If you wake and still notice pain, you may find it diminishing and becoming more tolerable as you drift off to sleep” is another bit of good advice.  Perhaps all the analgesic properties are due to self hypnosis, induced by the drug, so much more research is needed, but the subjective insistence as to its effectiveness should not be dismissed.

AuntieBS

 

Low levels tetrahydrocannabinol, or THC, the main psychoactive compound in marijuana, does reduce stress, but in a highly dose-dependent manner, new research confirms.

Source: Low-dose THC can relieve stress; more does just the opposite — ScienceDaily

 

It should also be pointed out that experience with cannabis plays a role in anxiety reduction.  An inexperienced user may experience paranoia and increased anxiety at a much lower dose than an experienced user.

AuntieBS

A natural signaling molecule that activates cannabinoid receptors in the brain plays a critical role in stress-resilience — the ability to adapt to repeated and acute exposures to traumatic stress.

Source: Natural chemical helps brain adapt to stress — ScienceDaily

Why is THC psychoactive and CBD is not? How can one cannabinoid alter the mind so profoundly, and the other seemingly not at all?

Source: CBD vs. THC: Why is CBD Not Psychoactive? | Leafly

For those suffering depression or anxiety, using cannabis for relief may not be the long-term answer, say researchers.

Source: This is your brain on (legal) cannabis: Researchers seek answers: For those suffering depression or anxiety, using cannabis for relief may not be the long-term answer — ScienceDaily

I am not sure what to make of this.  People FEEL better when using cannabis to self-medicate for depression or anxiety, but the researchers say that it doesn’t work as they people think it does.

“Doc, I feel better after self-medicating with cannabis.”

“No your don’t– you just think that you do”.

Could this be placebo effect?  Perhaps.  But, I’d say, if it doesn’t make the user any worse, and keeps them from using riskier drugs, then it could be a good thing.

AuntieBS