Archive for the ‘edibles’ Category

https://www.sciencedaily.com/releases/2018/05/180501085137.htm

Study shows up to 65 percent of older adults who use medical marijuana significantly reduced their chronic pain and dependence on opioid painkillers

I am aware of people who ate cannabis (~20-30g THC) in lieu of taking opiates when recovering from joint replacement surgeries.  They all touted longer relief (sleeping the night through instead of waking in pain and needing more opiates), as well as less constipation that opiates cause.  Most only used the cannabis at night, while continuing opiates during the day, but several ate more cannabis in the mornings, essentially getting up to 12 hours relief from a single edible dose.  A serendipitous side effect was that the cannabinoids also sped bone and nerve healing.

Another segment of the elderly population use ointments containing cannabis for relief from arthritis pain in their hands.  One used it on the lower back with success, while others got insufficient relief, possibly due to fatty tissues between the ointment and joints.

We truly need to de-schedule cannabis so that researchers can determine the plethora of health benefits from its use.

AuntieBS

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https://www.sciencedaily.com/releases/2018/04/180416085927.htm

Puh-leeze.  “However, the AASM has concluded that sleep apnea should be excluded from the list of chronic medical conditions for state medical cannabis programs due to unreliable delivery methods and insufficient evidence of treatment effectiveness, tolerability and safety.”  What a crock-o-shit.  Unreliable delivery methods?  What is unreliable about eating a given amount of THC?  I know of many who have self-medicated for pain, sleep, etc, very reliably by ingesting cannabis chocolate containing 10-30 mg THC, about two hours before expecting the desired effect.  True, tolerance quickly builds and within a month or two of daily ingestion like that, the dosage can be quadruple the virgin dose, but a month of abstinence restores the initial sensitivity just fine.  How can researchers not know this?

Evidence of treatment can be determined almost immediately, through a respiration monitor, even if subjective.  Safety is well known and tolerability can also be subjectively determined, but starting with low doses until the patient is acclimated and not fearful.

The tone of this paper smacks of Big Pharma, trying to cast fear, uncertainty, and doubt about a plant product which doesn’t generate obscene revenue for the pharmaceutical corporation.  They would much rather sell you a much more dangerous, less-effective pill, than to admit that a plant is not only safe but can be even more effective.

AuntieBS

https://www.sciencedaily.com/releases/2018/02/180215153923.htm

This paper cites the need for more, controlled research into medical cannabis uses and no one would argue that, but their usage and conclusions are questionable.  First, for pain relief, cannabis has an interesting property.  It only reduces pain slightly, but renders the patient not caring about it, thus making the pain more tolerable.  Unrealistic expectations also can interfere with analgesic properties.  Given cannabis’ sedative effects, it is often best used at night, when opiates would wear off, waking the patient, while cannabis lasts the night through.  Cannabis should be administered orally for a longer, time-release, effect, with 1-3 hours (2 typ) allowed before effects begin.

Further, some of the pain relief may be through defacto hypnosis, since cannabis can be considered a hypnotic drug, and therefore be heavily modulated by the patient’s mindset.  Inexperienced patients may feel anxiety, thereby rendering cannabis less effective for pain and sleep.

It is important for the prescribing physician to determine the patient’s familiarity and experience with cannabis before prescribing, as such patients often know subjectively how well it works for them.  Novice patients need be counseled on what cannabis does and does not do, with sufficient disclaimers so as to not give unrealistic expectations.  “This may make it easier for you to sleep through the pain and you might experience a bit of dizziness if you get up at night”, would be appropriate advice.  Note that pain is not mentioned.  “If you wake and still notice pain, you may find it diminishing and becoming more tolerable as you drift off to sleep” is another bit of good advice.  Perhaps all the analgesic properties are due to self hypnosis, induced by the drug, so much more research is needed, but the subjective insistence as to its effectiveness should not be dismissed.

AuntieBS

 

https://www.sciencedaily.com/releases/2018/02/180207090111.htm

Just guessing, I would assume that heroin addicts would augment their highs with strong cannabis doses, thereby using less opiate (stretching it for lower cost, longer availability) and thereby having fewer overdoses.  Medical cannabis is more often sold in stronger concentrates and infused candy for a more time-released effect, than is typically available in legal recreational cannabis markets.

Cannabis users that concurrently use alcohol, generally smoke less cannabis and drink less alcohol, than either alone.  Why would not the same relationship occur between those using cannabis and heroin, concurrently?

AuntieBS

https://www.sciencedaily.com/releases/2017/12/171212092100.htm

While smoking cannabis may be how researchers tested, or noted, the efficacy, eating cannabis provides a more even, time-release, and may therefore be a better alternative to smoking, which spikes blood content of the cannabinoids quickly, followed by a faster decline.

It may also help Alzheimer’s and Parkinson’s patients, too.

 

AuntieBS

https://www.sciencedaily.com/releases/2017/11/171106121300.htm

When cannabinoids activate signaling pathways in cancer cells they can stimulate a cell death mechanism called apoptosis, unleashing a potent anti-tumor effect.

And the parent article cited:

http://online.liebertpub.com/doi/10.1089/acm.2017.0016

Rick Simpson was one of the first to identify cannabis’ anti-cancer properties anecdotally.  The regimen he touted was to ingest as much cannabis as possible, ramping up as tolerance increases.  He used concentrated cannabis oil to treat himself and others.

It is important to note that smoking it does not get enough of the cannabinoids into the body; it must be orally ingested.  Searching for Rick Simpson will find his regimen and commentary.

AuntieBS

You wouldn’t think chili peppers and marijuana have much in common. But when eaten, both interact with the same receptor in our stomachs, according to a new paper. The research could lead to new therapies for diabetes and colitis, and opens up intriguing questions about the relationship between the immune system, the gut and the brain.

Source: Chili peppers and marijuana calm the gut, study suggests: The active ingredients in both hot peppers and cannabis calm the gut’s immune system — ScienceDaily