Archive for the ‘edibles’ Category

While smoking cannabis may be how researchers tested, or noted, the efficacy, eating cannabis provides a more even, time-release, and may therefore be a better alternative to smoking, which spikes blood content of the cannabinoids quickly, followed by a faster decline.

It may also help Alzheimer’s and Parkinson’s patients, too.




When cannabinoids activate signaling pathways in cancer cells they can stimulate a cell death mechanism called apoptosis, unleashing a potent anti-tumor effect.

And the parent article cited:

Rick Simpson was one of the first to identify cannabis’ anti-cancer properties anecdotally.  The regimen he touted was to ingest as much cannabis as possible, ramping up as tolerance increases.  He used concentrated cannabis oil to treat himself and others.

It is important to note that smoking it does not get enough of the cannabinoids into the body; it must be orally ingested.  Searching for Rick Simpson will find his regimen and commentary.


You wouldn’t think chili peppers and marijuana have much in common. But when eaten, both interact with the same receptor in our stomachs, according to a new paper. The research could lead to new therapies for diabetes and colitis, and opens up intriguing questions about the relationship between the immune system, the gut and the brain.

Source: Chili peppers and marijuana calm the gut, study suggests: The active ingredients in both hot peppers and cannabis calm the gut’s immune system — ScienceDaily

NORML’s mission is to move public opinion sufficiently to legalize the responsible use of marijuana by adults, and to serve as an advocate for consumers to assure they have access to high quality marijuana that is safe, convenient and affordable.

Source: – Working to Reform Marijuana Laws – – Working to Reform Marijuana Laws

Medical Marijuana Legalization Associated With Fewer Opioid-Related Hospitalizations

Medical Marijuana - Fewer Opioid-Related HospitalizationsSan Diego, CA: The enactment of statewide legislation permitting medical cannabis access by qualified patients is associated with a reduction in opioid-related hospitalization, according to data published online ahead of print in the journal Drug and Alcohol Dependence.

A researcher from the University of California at San Diego assessed the association between medical cannabis laws and hospitalizations related to opioid pain relievers. The author reported both immediate and longer-term reductions in opioid-related hospitalization following changes in law.

“This study demonstrated significant reductions on OPR- (opioid pain reliever) related hospitalizations associated with the implementation of medical marijuana policies. … We found reductions in OPR-related hospitalizations immediately after the year of policy implementation as well as delayed reductions in the third post-policy year.”

The author also dismissed contentions that liberalized marijuana laws were associated with any subsequent increase in marijuana-related hospital admissions, concluding: “While the interpretation of the results should remain cautious, this study suggested that medical marijuana policies were not associated with marijuana-related hospitalizations. Instead, the policies were unintendedly associated with substantial reductions in OPR related hospitalizations.”

The findings are consistent with those of other studies reporting that medical cannabis legalization is associated with lower rates of opioid abuse, mortality, and prescription drug spending.

For more information, please contact Paul Armentano, NORML Deputy Director, at: Full text of the study, “Medical marijuana policies and hospitalizations related to marijuana and opioid pain reliever,” appears in Drug and Alcohol Dependence.

Israeli Cabinet Endorses Marijuana Decriminalization Plan

Israeli Marijuana Decriminalization PlanJerusalem, Israel: Israeli lawmakers have signed off on legislation decriminalizing offenses involving the possession of personal use quantities of marijuana.

Under the new policy, first and second time possession offenders will face a fine, but no criminal penalties.

“The Cabinet approval is an important step on the way to implementing the new policy that will put emphasis on explaining and treating rather than on criminal enforcement,” explained Israeli Public Security Minister Gilad Erdan.

The medical production and distribution of cannabis for medical purposes is already legally permitted in Israel as part of a program governed by the Ministry of Health. About 25,000 Israelis receive medical marijuana as part of this program.

For more information, please contact Paul Armentano, NORML Deputy Director, at:

Study: CBD-Dominant Cannabis Extracts Reduce Seizure Frequency

CBD Cannabis Extracts Reduce SeizuresFalmouth, ME: The administration of whole-plant cannabis extracts rich in the cannabinoid cannabidol (CBD) is associated with reduced seizure frequency in patients with refractory epilepsy, according to data published online ahead of print in the journal Epilepsy & Behavior.

Researchers performed a retrospective chart review of the clinical records of 272 patients who were taking whole-plant CBD extracts.

Eighty-six percent of those treated observed some clinical benefit (a reduction in seizure frequency) while ten percent experienced a complete clinical response. The remaining patients were either not responsive to treatment or reported an exacerbation of seizures during therapy.

Beneficial side effects, such as improved mood, better sleep quality, and increased appetite were reported.

“The cannabinoids’ novel mechanisms of action are an attractive consideration for possible seizure control,” authors concluded. “In patients with refractory epilepsy that have a low likelihood of responding to a subsequent AED (anti-epileptic drug), a trial of artisanal cannabis formulas may be indicated.”

For more information, please contact Paul Armentano, NORML Deputy Director, at: Full text of the study, “The current status of artisanal cannabis for the treatment of epilepsy in the United States,” appears in Epilepsy & Behavior. Additional data regarding the efficacy of cannabinoids as anticonvulsants appears in NORML’s library.

Pennsylvania: Auditor General Says State Lawmakers Should Regulate The Marijuana Market

Pennsylvania Should Regulate MarijuanaHarrisburg, PA: Pennsylvania’s auditor general on Monday publicly advocated for the legalization and taxation of retail marijuana sales, arguing that such a policy would bring new jobs and tax revenue to the state.

Speaking at a news conference at the state capitol, Auditor General Eugene DePasquale said: “The regulation and taxation of the marijuana train has rumbled out of the station, and it is time to add a stop in the Commonwealth of Pennsylvania. I make this recommendation because it is a more sane policy to deal with a critical issue facing the state. Other states are already taking advantage of the opportunity for massive job creation and savings from reduced arrests and criminal prosecutions. In addition, it would generate hundreds of millions of dollars each year that could help tackle Pennsylvania’s budget problems.”

However, Gov. Tom Wolf said that state lawmakers should not go forward with regulating the adult use marijuana market at this time. Instead, he expressed support for decriminalizing the possession and personal use of the plant.

For more information, please contact Justin Strekal, NORML Political Director, at (202) 483-5500 or visit:

NORML and the NORML Foundation: 1100 H Street NW, Suite 830, Washington DC, 20005
Tel: (202) 483-5500 • Fax: (202) 483-0057 • Email:

I have consumed a lot of edibles and consumables over the years. Like most Oregonians, I was consuming edibles well before there were stores. I vividly remember the… #decarboxylate #decarboxylation

Source: What Is Marijuana Decarboxylation And How Do You Do It? | Weed News


The average pot enthusiast is more likely to dump an ounce of mids into some brownie batter than whip up something digestible and effective, so we asked the author of The 420 Gourmet, to share some of his best tips to up your cannabis cooking.

Source: The ‘Julia Child of Weed’ Explains How You’re Making Edibles Wrong | VICE | United States

From this synopsis, the author states that putting cannabis into your brownie mix is likely to make you sick.  Not true!  And the math is simple:  1 oz (28g) of 21% THC contains: 28 * .21 = 5.88g of THC in that ounce of cannabis.  Know your dosage:  Mine was 50mg THC to treat my malady.  So, 5.88g is 5880 mg.  Divide this by the dosage: 5880/50 = 117.6 doses, each with 50mg.  Or is it?

One problem is that that raw cannabis’ THC is in a carboxylated form, THCa, and requires heat to decarboxylate it:


Grinding the cannabis finely, using a coffee grinder, then putting the powder into a dry jar, then float the sealed jar in a pot of boiling water, with a lid covering it, is a simple way to decarboxylate it.  This will ensure that the cannabis is dry, but subject to 100°C heat.  I did this for 100-120 minutes, then dumped the decarboxylated powder into about 24oz melted chocolate (with 3 TBSP coconut oil to maintain consistency) that is mixed THOROUGHLY to ensure homogeneity, and then divided into the 117 (120 is close enough) doses.

The resulting chocolates each provide the desired 50mg dose with a slight cannabis taste, not objectionable at all.  The author’s concerns about pesticides are valid, so be sure to know your source (usually monitored in states where medical cannabis is legal).

Also, if you eat your 50mg doses for any length of time, you will develop tolerance.  Within 3 months, my theraputic dose because 100mg, so it was necessary to eat 2 of the chocolates.  But, abstaining from cannabis for ~30 days restores the tolerance down to virgin levels.

Lastly, BE CAREFUL.  The fulle effects of eating cannabis do not manifest themselves for 30-180 minutes, with about 120 minutes being the usual, so BE PATIENT, lest you OD.  You cannot fatally OD, but if you eat significantly more than your normal dosage, the effects can be most unpleasant, and just eating food and relaxing to wait it out are the usual advice given.



Researchers have discovered the benefits of THC in the brain

Source: Could A Chemical Found in Marijuana Be A Treatment For Alzheimer’s Disease? | Popular Science

The NIH confirmed efficacy in tiny, sub-intoxicating, doses.  I have witnessed noticeable improvement from the patient eating 3mg THC daily– an amount FAR less than can be felt.