Posts Tagged ‘cannabis’

https://www.sciencedaily.com/releases/2019/02/190211083204.htm

A seventy year old man, without cannabis experience, ate 90mg THC, or about 3-10 times the normal dosage, depending upon his body weight.  So, he got seriously buzzed and freaked out.  Panic attack!  It was THAT that caused tachycardia and likely constrictions in blood flow due to adrenaline and panic.  That’s all.  It’s disingenuous to declare the cannabis as causal, even though it indirectly may be.  The point is that cannabis does not cause cardiovascular problems, but panic attacks apparently do.  What if the guy saw something on television that freaked him out and caused a panic attack?  Would these “researchers” declare television to be dangerous to patients with cardiovascular disease?  Only if they had a hidden agenda.

Cannabis is generally relaxing, but blood pressure can be slightly raised while under its effects.  Research shows that cannabis is a vasodilator, if anything, so it should be beneficial to cardiovascular patients.  This paper implies otherwise, but did correctly state: “The patient’s cardiac event was likely triggered by unexpected strain on his body from anxiety and fearful hallucinations caused by the unusually large amount of THC he ingested. His sympathetic nervous system was stimulated, causing increased cardiac output with tachycardia, hypertension, and catecholamine (stress hormone) release. After the psychotropic effects of the drug wore off, and his hallucinations ended, his chest pain stopped.”  [emphasis mine]

So, this really has nothing to do with cannabis, but is about fear/panic, which could be caused by many different subjective experiences.  What if the man had eaten peanuts with dinner– would the researcher’s declare that he had a peanut allergy?  Remember– “correlation is not causality”.  Further, the paper talked about “…since the THC content of the substance had increased significantly from three percent to 12 percent.”  This meme is common to BULLSHIT papers which tout the “danger from increased potency cannabis”.  Increased potency simply means that less is needed.  Just as you don’t drink vodka by the pint, like you do beer, you don’t smoke an entire joint like people did 50 years ago.  One or two hits usually suffices, just like a shot of vodka, not a liter.  So, anytime the “increased potency” meme is used, it discredits the paper’s authors because it indicates either extreme naivete’ or an anti-cannabis agenda.

AuntieBS

https://www.sciencedaily.com/releases/2018/09/180910173731.htm

Very effective medication for many conditions.

AuntieBS

https://www.sciencedaily.com/releases/2018/07/180723132251.htm

AuntieBS is not a neuroscientist, so to flat-out declare this to be bullshit is out of her league.  But, such “studies” should be viewed with a jaundiced eye, because there is so much negative pressure against cannabis from Big Pharma, so see its use as reducing their profits.

When you read reports of modern cannabis strains being more potent, be wary.  Instead of smoking entire joints, the modern cannabis user enjoys just a toke or two, akin to a shot or two of vodka vs a six pack of beer.  The cannabis ingestion level may be the same, but the tars and combustion byproducts is much less with stronger strains.  Having said that, there are no details as to the amount of cannabis given to the test mice, and how that would extrapolate to human use.  If a human got as wasted as they could possibly be and remain awake, there may not be much remembered.  But, the amount of intoxication under “normal” use, is much less and long-term memory is not affected.

So, I question the veracity of this assertion and remain unconvinced, though I cannot discount it 100%.  As with most things, moderation is a good concept.

AuntieBS

https://www.consumerreports.org/marijuana/what-is-cbd-what-to-know-about-this-cannabis-product/

 

https://www.sciencedaily.com/releases/2018/05/180510145924.htm

 

AuntieBS

https://www.sciencedaily.com/releases/2018/05/180510162925.htm

There is a lot of anecodotal evidence as to cannabis action against cancers of various kinds.  And, this is furthere supported by scientific research showing that a type of brain cancer, glioma, is indeed killed by cannabis, in vitro, at least.

Until Big Pharms stops trying to interfere in research, and our politicians remove their heads from the lobbyist’s behinds, there can be no legal research in this country because cannabis is scheduled I, along with heroin, methamphetamine, and crack cocaine.

AuntieBS

Study: Cannabis Use Associated With Lower Risk Of Atrial Fibrillation Among Patients Hospitalized For Heart Failure

Cannabis Use Lower Risk Of Atrial FibrillationEnglewood, NJ: Cannabis exposure is associated with lower instances of atrial fibrillation (arrhythmia) in patients hospitalized for heart failure, according to data published in the American Journal of Cardiology.

A team of investigators from Seton Hall University, the University of Alabama at Birmingham, and elsewhere assessed the relationship between cannabis exposure and atrial fibrillation in a cohort of nearly four million patients hospitalized in 2014 for heart failure.

Compared to matched controls, “Cannabis users have lower odds of AF [than do] nonusers, which was not explained by co-morbid conditions, age, insurance type, [or] socioeconomic status,” authors concluded.

A prior analysis by the team similarly reported that cannabis exposure lowered the risk of atrial fibrillation and also reduced in-hospital mortality in heart failure patients.

Other studies have similarly reported that marijuana-exposed patients are less likely than non-users to die when hospitalized for burns and other forms of severe trauma, certain types of orthopedic surgeries, and traumatic brain injury.

For more information, contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, “Relation of cannabis use and atrial fibrillation among patients hospitalized for heart failure,” appears in the American Journal of Cardiology.

https://www.sciencedaily.com/releases/2018/05/180501085137.htm

Study shows up to 65 percent of older adults who use medical marijuana significantly reduced their chronic pain and dependence on opioid painkillers

I am aware of people who ate cannabis (~20-30g THC) in lieu of taking opiates when recovering from joint replacement surgeries.  They all touted longer relief (sleeping the night through instead of waking in pain and needing more opiates), as well as less constipation that opiates cause.  Most only used the cannabis at night, while continuing opiates during the day, but several ate more cannabis in the mornings, essentially getting up to 12 hours relief from a single edible dose.  A serendipitous side effect was that the cannabinoids also sped bone and nerve healing.

Another segment of the elderly population use ointments containing cannabis for relief from arthritis pain in their hands.  One used it on the lower back with success, while others got insufficient relief, possibly due to fatty tissues between the ointment and joints.

We truly need to de-schedule cannabis so that researchers can determine the plethora of health benefits from its use.

AuntieBS

Marijuana Use for HeartBergenfield, NJ: Heart failure patients with a history of cannabis use possess reduced odds of in-hospital mortality compared to similarly matched controls, according to data published online in the journal Circulation.

Investigators assessed data from over six million heart failure patients over a seven-year period. Patients with a history of cannabis use were less likely to suffer from atrial fibrillation (irregular heartbeat), experienced shorter hospital stays, and were less likely to die during hospitalization as compared to non-users.

“Our study showed that cannabis use lowered the odds of atrial fibrillation in patients with heart failure,” authors concluded. “There was also reduced in-hospital mortality among patients admitted for the primary diagnosis of heart failure in DU (cannabis dependent users) and NDU (non-dependent cannabis users) which was not explained by comorbid conditions and demographic data. This study provides important opportunity to explore the preventive mechanism of cannabis on atrial fibrillation and its therapeutic potential in heart failure patients.”

Prior studies have similarly reported increased survival rates among marijuana-positive patients hospitalized for traumaTBI (traumatic brain injury), and heart attacks.

For more information, contact Paul Armentano, NORML Deputy Director, at: paul@norml.org. Full text of the study, “Among patients with heart failure, cannabis is associated with reduced occurrence of atrial fibrillation and in-hospital mortality: Evidence from the Nationwide Survey 2007-2014.”

Survey: Many Medical Cannabis Patients Cease Using Opioids

Thursday, 16 November 2017

Medical Marijuana Less OpioidsChicago, IL: More than two out of three medical marijuana patients substitute cannabis in place of opioids, according to survey data compiled by Aclara Research, a Chicago-based consulting firm.

Sixty-seven percent of respondents reported that they ceased their opioid use after initiating cannabis therapy. Twenty-nine percent of respondents said that cannabis allowed them to decrease their use of opioids.

The findings are similar to those of prior surveys concluding that patients who use cannabis therapeutically typically reduce or cease their use of opioids and other prescription pharmaceuticals.

According to an October 21 academic paper published on SSRN.com, the enactment of medical marijuana access laws is associated with a $2.47 decrease in per person prescribed opioid spending among those between the ages of 18 and 39. Previous studies – such as those herehere, and here – have drawn similar conclusions.

On November 1, members of President Trump’s opioid commission rejected the notion that cannabis access is associated with reduced rates of opioid abuse and mortality. By contrast, the US National Institute on Drug Abuse acknowledges that available studies “cumulatively suggest that medical marijuana products may have a role in reducing the use of opioids.”

For more information, contact Paul Armentano, NORML Deputy Director, at: paul@norml.org.